1. Management of Suspect/Probable cases (hospital/community) a. Any person who develops influenza like illness (ILI) should be strongly encouraged to self-isolate in their home for 10 days after the onset of illness; b. To instruct the suspect case(s) for home isolation or in isolation at hospital till the result of test is available; c. To designate single household/family member as caregiver; d. The case should be kept in a separate room; if not positive, to keep the patient in a separate bed partitioned by curtain; e. The care givers should maintain a minimum distance of 6 feet from the case; f. While in home isolation, case(s) and other household members should be given infection control instructions, including i. frequent hand washing with soap and water; ii. cover mouth and nose with mask; iii. If a face mask is not available tissue/handkerchief/piece of clothe/’sarianchol’/ ‘gamcha’/ shirt’s sleeve/scarf may be used to cover cough and sneeze; iv. To practice spitting at defined places; v. To avoid touching the eyes, nose, and mouth; vi. If the case(s) needs to go outside home (e.g., to seek medical care), he or she should wear a face mask; g. Provide supportive treatment as necessary; i. Supportive treatment consists of bed rest, increased fluid consumption, antihistamine, antipyretics and analgesics (e.g., paracetamol and non steroidal anti-inflammatory drugs) for fever and myalgia; ii. If secondary bacterial infection is suspected, antibiotic may be added iii. Severe cases may require hospitalization and other supportive measures; h. If test result is negative but symptoms do not subside to continue home isolation for up to 10 days after onset of symptoms; i. Case(s) should wear mask during transportation and hospital isolation. 2. Management of confirmed cases a. If the test result is positive, start antiviral therapy as soon as possible; b. Keep patient in home confinement or isolation at hospital for up to 10 days after onset of symptoms; c. Give supportive treatment when indicated; d. If severely ill and need emergency intervention refer patient to hospital having isolation facilities (National Institute for Disease of Chest and Hospital [NIDCH], Mohakhali, Dhaka, District Sadar Hospital and Medical College Hospital); 3. Management of patient in health care setting: Hospital/ clinics a. To manage the patient in the isolation unit /ward b. Suctioning or intubation should be performed in a procedure room with negativepressure air handling; c. Patients should wear a surgical mask when outside their room; d. To encourage patients to wash their hands frequently and to follow respiratory hygiene practices; e. Glasses and Cups and other utensils used by the ill person should be washed with soap and water before use by other persons. f. Health care personnel should wash their hands with soap and water immediately after removing gloves and other equipment and after any contact with respiratory secretions; g. Personnel providing care to or collecting clinical specimens from patients should wear disposable nonsterile gloves, gowns, and eye protection (eg, goggles); h. Personnel engaged in aerosol-generating activities (eg, collection of clinical specimens, endotracheal intubation, nebulizer treatment, and bronchoscopy) and/or resuscitation involving emergency intubation or cardiac pulmonary resuscitation should wear a fit-tested disposable N95 respirator. i. To maintain infection control guidelines during patient management j. Frequent hand washing with soap by care givers (Health personnel and Family members). Alcohol based rub may be used if hands are dry and not soiled; 4. Antiviral use for pandemic influenza a. Drugs indicated for treatment of Pandemic Influenza include neuraminidase inhibitors (ie, oseltamivir and zanamivir). Currently, oseltamivir is the drug of choice; b. Oseltamivir is available as 75-mg oral capsules and as a oral powder for suspension that contains 12 mg/mL after reconstitution. c. Adult dose i. Treatment for acute illness: 75 mg orally bid for 5 days ii. Prophylaxis: 75 mg orally daily for 7 days (Please refer to duration of prophylaxis specific for specific situation) d. Pediatric dose i. Treatment for children age